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SRS of Brain Tumors

  • Stereotactic Radiosurgery (SRS) is a highly advanced, non-invasive radiation technique that delivers a very high dose of focused radiation to a brain tumor in a single session (or up to 3–5 sessions, known as fractionated SRS).

    Despite the name “radiosurgery,” there is no incision, no anesthesia, and no operating room. The word “surgery” is used because SRS delivers surgical-level precision, often with sub-millimetre accuracy.

    SRS is one of the most effective treatments for small brain tumors, recurrent disease, and selected functional disorders, offering excellent local control while sparing healthy brain tissue.

  • SRS combines several cutting-edge technologies:

    • Stereotactic head immobilization (frame-based or frameless)

    • MRI / CT fusion imaging for ultra-accurate tumor targeting

    • Image-Guided Radiotherapy (IGRT) for real-time verification

    • High-precision beam shaping (using LINAC, Gamma Knife, or CyberKnife)

    These allow clinicians to deliver a highly ablative radiation dose directly to the tumor with remarkable precision.

  • SRS is ideal for small and well-defined brain lesions. It can be used for both primary and metastatic tumors as well as certain benign conditions.

    Common Indications:

    • Brain metastases (from lung, breast, melanoma, etc.)

    • Meningioma

    • Acoustic Schwannoma (Vestibular Schwannoma)

    • Pituitary adenoma

    • Recurrent or residual glioma

    • Arteriovenous malformations (AVMs)

    • Functional disorders (e.g., Trigeminal Neuralgia)

    • SRS is especially valuable when surgery is:

    • High-risk due to tumor location (near brainstem, optic nerve, eloquent cortex)

    • Not preferred by the patient

    • Contraindicated due to age or comorbidities

    • Required for multiple lesions (e.g., multiple brain metastases)

    • SRS preserves neurological function and requires no hospital stay, allowing patients to return home the same day.

    • Non-invasive, painless procedure

    • No incision, no stitches, no ICU

    • Preserves critical brain structures

    • Outpatient, short treatment time

    • High local tumor control

    • Option for re-irradiation if disease recurs

    • Can treat multiple metastases in a single sitting

    • Most patients tolerate SRS extremely well. Possible effects include:

    • Mild headache or nausea

    • Temporary swelling around the treated area

    • Rare risk of radiation necrosis

    • Temporary balance, vision, or memory changes (depending on tumor site)

    • These are minimized with modern planning, imaging, and dose constraints.

    • SRS for brain tumors has transformed neuro-oncology by offering a curative, incision-less alternative to open brain surgery in selected patients. With its unmatched precision, excellent tumor control, and minimal downtime, SRS enables patients to maintain both survival and quality of life.

    • As technology continues to advance, SRS remains one of the most powerful tools in modern brain tumor management — combining accuracy, safety, and comfort in a single therapeutic platform.

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